Sculptor, assemblage artist, painter, and printmaker Claudine Paluzzi was born Claudine Kelsey on October 12, 1931, in Richmond, Indiana. Upon graduating high school in 1949 she was awarded a scholarship to attend the John Herron School of Art (now the Herron School of Art and Design at Indiana Univeristy), where she earned her Bachelors in Fine Arts in 1953. Around this time she married fellow Herron student Rinaldo Paluzzi, with whom she would travel to Italy in 1957, along with their three children, after Rinaldo was awarded a Tiffany Grant to pursue art in Rome. They remained there for a year before returning to Indianapolis, but they would go back to live and work in Italy and Paris through the mid-1960s. 

When she returned to the U.S. she took up a job as a teacher with the Indianapolis Art League (now the Art Center), and earned her Masters in Art Education at Indiana University. She later taught at the Indianapolis Art Museum, the Indiana Deaf School, Marion College, and was an instructor for thirty years at Indiana University - Purdue University Indianapolis. She was the first artist in residence sponsored by the Indiana State Arts Commission, receiving a $10,000 grant from the commission in 1972 to mentor in several schools throughout Indiana. In addition to her personal fine art output and teaching, she worked as a court artist for Channel 13 News in Indianapolis; among the more noted cases she captured was the infamous Ford Motor Company Pinto Trial. 

Paluzzi worked in everything from Abstraction to Folk/Primitive to Pop to Hyperrealism, and despite a prolific output and keen talent, her range of styles likely made her work difficult to categorize. As such, she gained less notice than many of her contemporaries, including her husband (later divorced), Rinaldo Paluzzi - though numerous records of her work can be found in auction records from throughout the U.S. Paluzzi exhibited at Indiana University, Purdue University, the Indiana State House, the Hoozier Salon, and more. She would win awards from the Indiana Print Show, Hoosier Salon, Ball State Drawing and Sculpture Show, and more.

She died on September 22, 2018, in Indianapolis. Her work is included in the collection of the Indianapolis Museum of Art.

Selected Exhibitions:
1959: McGuire Galleries, Indianapolis (solo)
1962: The 1444 Gallery, Indianapolis (solo)
1963: Two-person show with Rinaldo Paluzzi, Park Avenue Galleries, Mt. Kisco, NY
1968: Purdue University, group show, Indiana Artists Club
1977: "Claudine Paluzzi", Jewish Community Center, Indianapolis (solo)